Factors Affecting the in Vitro Dissolution of Cobalt Oxide
نویسندگان
چکیده
منابع مشابه
Factors affecting the in vitro dissolution of cobalt oxide.
In a recent interspecies comparison of the lung clearance of cobalt oxide (57Co3O4), differences of up to 4-fold were found in the translocation rates of 57Co to blood between seven different animal species, including man. This study investigated some factors that could influence the dissolution of this material in vitro. The effect of bicarbonate and citrate concentrations (over physiological ...
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Solubility of drug plays a prime role in controlling its dissolution from dosage form. Aqueous solubility of drug is a major factor that determines its dissolution rate. Minimum aqueous solubility of 1% is required to avoid potential solubility limited absorption problems. Studies of 45 compound of different chemical classes and a wide range of solubilities revealed that initial dissolution rat...
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In vitro dissolution of uranium oxide by baboon alveolar macrophages.
In vitro cellular dissolution tests for insoluble forms of uranium oxide are technically difficult with conventional methodology using adherent alveolar macrophages. The limited number of cells per flask and the slow dissolution rate in a large volume of nutritive medium are obvious restricting factors. Macrophages in suspension cannot be substituted because they represent different and poorly ...
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ژورنال
عنوان ژورنال: Environmental Health Perspectives
سال: 1992
ISSN: 0091-6765
DOI: 10.2307/3431337